Successful Treatment of Erythrodermic Mycosis Fungoides with Mogamulizumab Followed by Etoposide Monotherapy

نویسندگان

  • Taku Fujimura
  • Kayo Tanita
  • Yota Sato
  • Yumi Kambayashi
  • Sadanori Furudate
  • Akira Tsukada
  • Akira Hashimoto
  • Setsuya Aiba
چکیده

Mogamulizumab induces cytotoxicity against CCR4+ lymphoma cells by antibody-dependent cell-mediated cytotoxicity in advanced cutaneous T-cell lymphoma patients. Since the efficacy of mogamulizumab in mycosis fungoides (28.6%) is lower than that in Sézary syndrome (47.1%), reagents that enhance the antitumor immune response induced by mogamulizumab are needed to further optimize its use for the treatment of erythrodermic mycosis fungoides. In this report, we present a case of erythrodermic mycosis fungoides successfully treated with mogamulizumab followed by etoposide monotherapy.

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عنوان ژورنال:

دوره 11  شماره 

صفحات  -

تاریخ انتشار 2018